Click here to read about the MTA Study that provided data for these findings: Association Between Stimulant Treatment and Substance Use Through Adolescence Into Early Adulthood.

Principal Investigators: Brooke Molina, PhD and Sarah Pedersen, PhD

Funding Source: NIAAA

The Pittsburgh ADHD Longitudinal Study (PALS) is one of the largest long-term studies ever conducted in which children diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD) are followed through adolescence into adulthood.  The investigators are Drs. Brooke Molina and Sarah Pedersen, University of Pittsburgh, and Dr. William E. Pelham, Jr., Florida International University.  Many other investigators have provided their expertise and support over the years.

Since 1999, the study has been following approximately 400 individuals diagnosed with ADHD in childhood who received treatment through the Children's Summer Day Treatment Program for ADHD in Pittsburgh (Western Psychiatric Institute & Clinic, University of Pittsburgh).  An additional 240 individuals without ADHD are also participating for comparison purposes. 

The purpose of the study is to learn more about the development of children diagnosed with ADHD in the 1980s and 1990s and to answer major questions in the field about factors that affect longterm course.  We study educational and occupational functioning, social and family relations, drug and alcohol use, and the extent to which childhood problems may or may not have persisted into adolescence and young adulthood.  A unique feature of the study is the ability to answer questions about healthy functioning in adulthood as a function of childhood characteristics, such as severity of problems in childhood or treatment history.

In 2020, the study was funded for an additional five years, and 90% of the original participant group remain involved.  As our study participants age through their 30s and into their early 40s, we will be able to examine the degree to which experiences related to ADHD in adolescence and early adulthood continue as employment and family responsibilities increase.  Individuals will participate in two assessments, spaced two years apart.  In addition to our standard surveys that assess many domains of functioning, we have added an innovative brief cellphone-based assessment that participants will complete throughout the day for 10 days.  Combining these new methods is a novel approach that will allow us to better understand long-term functioning and in-the-moment experiences that contribute to overall outcomes.

PALS study participants may call the PALS scheduling line at 412-246-5656 to speak to a staff person or to schedule a study appointment. For more information about PALS, please contact the study coordinator, Tara Draper, at 412-246-6977 or by email.